MIT Technology Review is reporting that a company called Generation Lab is promoting a new injectable "rejuvenation treatment" called 1-Generation, which it claims can block the systemic spread of aging, reawaken the body's repair mechanisms and restore health and youth to multiple tissues. The publication said the treatment is an injectable combination of two existing drugs, though Generation Lab has not disclosed their names.
Irina Conboy, Generation Lab's scientific founder, is known for her work on parabiosis, a practice involving joining the circulatory systems of old and young lab animals to observe rejuvenating effects. Conboy says she has now achieved similar youthful effects in humans using the drug combination, without the need for blood exchange. She and other insiders, including CEO Alina Su, claim to have experienced benefits such as increased energy and mental clarity.
However, MIT Technology Review noted several red flags regarding Generation Lab's approach to evidence. Su said the company plans a larger study where subjects will pay for enrollment, a practice often viewed as a sales channel rather than scientific pursuit. The trial will also be led by longevity doctors who practice alternative medicine, including Matt Cook, who previously recommended COVID-19 treatments designated as "fraudulent" by the FDA. Cook, who took the combination, expressed surprise at its effects but also stated he has "many more questions than I have answers."
Longevity doctor Jeffrey Gladden, whose clinic will be involved in the study, expressed both skepticism and optimism. Su said the drug names are confidential to avoid imitators, as Generation Lab does not own the molecules and seeks a short period of FDA exclusivity for a new use of existing drugs. The company is hosting an invite-only event featuring notable figures like Harvard synthetic biologist George Church, who said in an email he was also offered the drug combination.
Full Article: A startup claims it’s found a drug to make your blood young