5/10/17Antibiotic breakthrough: Team discovers how to overcome gram-negative bacterial defenses
Scientists report that they now know how to build a molecular Trojan horse that can penetrate gram-negative bacteria, solving a problem that for decades has stalled the development of effective new antibiotics against these increasingly drug-resistant microbes. The findings appear in the journal Nature.
Led by University of Illinois chemistry professor Paul Hergenrother, the scientists tested their approach by modifying a drug that kills only gram-positive bacteria, which lack the rugged outer cell membrane that characterizes gram-negative microbes and makes them so difficult to combat. The modifications converted the drug into a broad-spectrum antibiotic that could also kill gram-negatives, the team reports.more...
Research News | Campus News | Faculty Interviews | Videos | About
ILLINOIS NEWS BUREAU
507 East Green Street, Suite 345, Champaign, IL 61820 217.333.1085
(w) news.illinois.edu (e) email@example.com
Founded in 1867 as a land grant institution, the University of Illinois at Urbana-Champaign is celebrating 150 years of transformative experiences and heralding an ambitious vision for the future through learning, discovery and public engagement. More information on our sesquicentennial milestones and festivities is available at 150.illinois.edu.